In the women's singles action at the 2016 US Open on Friday, Germany's Angelique Kerber, Denmark's Caroline Wozniacki, Italian seventh 7 seed Roberta Vinci, Britain's Johanna Konta and Czech Petra Kvitova all moved into the Round of 16 with comfortable victories.

World No.2 Kerber made quick work of American qualifier Catherine Bellis with a 6-1, 6-1 romp to book a place in the fourth round, where she'll play former No.2 Kvitova, who moved past Ukrainian Elina Svitolina 6-3, 6-4.

Veteran Indian star Leander Paes and his German partner Andre Begemann crashed out of the men's doubles competition at the US Open with a first round loss to Stephane Robert of France and Dudi Sela of Israel in Flushing Meadows, New York on Friday. The Indo-German duo battled hard before going down 6-2, 5-7, 4-6 in a shade under 2 hours.

Robert and Sela will now take on Lukasz Kubot of Poland and Alexander Peya of Austria in the second round. The 12th seeded Polish-Austrian team defeated Americans Eric Quigley and Nicolas Meister 7-6, 6-1 in their opening round encounter.

World No.2 Andy Murray and Japan's Kei Nishikori advanced to the third round after defeating their respective opponents at the US Open in Flushing Meadows, New York.

Murray on Thursday brushed aside the challenge of Spain's Marcel Granollers 6-4, 6-1, 6-4 to advance, while Japan's Kei Nishikori battled past Russia's Karen Khachanov 6-4, 4-6, 6-4, 6-3.

Spanish tennis great Rafael Nadal raced away with the first seven games of the match to set up a routine straight-sets victory over Italian veteran Andreas Seppi in the second round of the US Open.

Nadal's 6-0, 7-5, 6-1 win was also marked by the historic closure of the retractable roof on Arthur Ashe Stadium for the first time in match play at Flushing Meadows in New York on Wednesday.

American qualifier Ryan Harrison has pulled off the biggest upset so far at the ongoing US Open, stunning fifth-seeded Canadian Milos Raonic 6-7 (4-7), 7-5, 7-5, 6-1 in second-round tennis action.

Raonic appeared to be in total control when he went up a break in the third set, but leg cramps began severely hampering his movement and allowed Harrison to climb back into the match on Wednesday.

Indian tennis stars Leander Paes, Sania Mirza and Rohan Bopanna all began their US Open campaigns on a positive note, winning their respective opening round matches at Flushing Meadows, New York.

Bopanna kicked off India's day with a sweat-inducing 6-3, 6-7 (3), 6-3 win with his Danish partner Frederik Nielsen over 16th seeds Radek Stepanek and Nenad Zimonjic in the first round men's doubles on Wednesday.

Top seed Serena Williams outplayed unseeded Russia's Ekaterina Makarova 6-3, 6-3 in a potentially tricky first round encounter at the US Open in Flushing Meadows, New York on Tuesday.

Williams needed to be right on the money from the start given the quality of opposition she was up against, and she powered down 12 aces to demolish Makarova in 63 minutes.